Coding
Part:BBa_K2065003:Experience
Designed by: Tom van Sonsbeek Group: iGEM16_TU-Eindhoven (2016-10-07)
iGEM TU Eindhoven 2016
Applications of BBa_K2065003
iGEM TU Eindhoven planned to use CT52-Caspase 9 on testing the effectivity of a homotetrameric T14-3-3 scaffold protein. Another use of CT52-Caspase 9 in our project was testing whether a T14-3-3 mediated kill switch could viable. In figure 1 a schematic representation of an measurement using CT52-Caspase 9 is depicted which could provide these results.
Figure 1: the tetrameric scaffold increasing local concentrations of Caspase-9 better than a dimer, inducing the apoptosis pathway more efficiently.
User Reviews
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